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1. The cellular component consists of three major cell types, all of which arise from hematopoietic stem cells located primarily in the bone marrow: red blood cells (RBCs), white blood cells (WBCs), and platelets.
2. Platelets are the other major cellular component of blood and are small anucleate cells produced from megakaryocytes in the bone marrow.
3. Left shift (or blood shift): an increase in immature precursor cells (e.g., increase in band neutrophils with rod-shaped nuclei in response to acute inflammation) in the blood.
4. It is composed of stromal cells and stem cells, which are the progenitors of all five blood cell lineages.
5. This learning card provides an overview of the production, morphology, and most important functions of blood cells.
6. White blood cells (WBC, leukocytes) take the form of either granulocytes or lymphocytes.
7. Red blood cells (RBC, erythrocytes) are hemoglobin-carrying cells that primarily transport oxygen.
8. Blood has many functions, including transporting oxygen, regulating body temperature, and supporting the immune system.
9. It also filters aging RBCs and houses immune cells (e.g., plasma cells).
10. Human blood is composed of ∼45% cellular components and ∼55% plasma.
11. Granulocytes are part of the innate immune system and play a key role in the immune response to bacteria, fungi, and parasites.
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